Ciliated micropillars for the microfluidic-based isolation of nanoscale lipid vesicles.

نویسندگان

  • Zongxing Wang
  • Hung-jen Wu
  • Daniel Fine
  • Jeffrey Schmulen
  • Ye Hu
  • Biana Godin
  • John X J Zhang
  • Xuewu Liu
چکیده

We fabricated a microfluidic device consisting of ciliated micropillars, forming a porous silicon nanowire-on-micropillar structure. We demonstrated that the prototype device can preferentially trap exosome-like lipid vesicles, while simultaneously filtering out proteins and cell debris. Trapped lipid vesicles can be recovered intact by dissolving the porous nanowires in PBS buffer.

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عنوان ژورنال:
  • Lab on a chip

دوره 13 15  شماره 

صفحات  -

تاریخ انتشار 2013